Air Freight logistics is an open cold chain and this is a fact. The entire logistic chain is made of different actors, working together in a complex commercial relationship matrix maintaining the pharmaceutical integrity within the required temperature requirements. Many variables need to be managed to be successful. Critical control points must be risk assessed and controlled. We will analyze those critical control points and the involved documents, special handling codes and labels. We are going also to discuss the GDP requirements and which chapters are impacting to logistic providers part of the air freight logistic chain. The scope of this session is to explain the main requirements coming from the pharmaceutical industry and how they impact the logistic company. Additionally, you will see what active and hybrid containers are. What differentiates passive packaging system and what is the scope of a thermal cover. We will give an answer to different kinds of different temperature monitoring systems, and have a look into what different devices are on the market and what are they for. The final part of the training will go through risk management basic requirements and how an FMEA method should be used and implemented correctly.